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1) GENERAL Firstly, this report provides the usual forecast projections of the likely growth of HIV/AIDS in the UK, but concentrates on the possible likely growth of HIV cases in the UK within the foreseeable future until the end of year 2015. Secondly, it is time that someone in authority took an interest in the method and computer program used by the author. Although the method is fully described in web site www.AIDSCJDUK.info it requires a considerable effort to produce an easily used program from it. The author already has a refined program for the Sinclair Spectrum computer and has partly rewritten it for a PC. He has also, through the years, built up an extensive library of AIDS data and forecasts since 1987. He is now over 80 years old, so cannot guarantee to continue until 2015 or beyond. The program and information can be made available if someone can be given the task of perfecting the program for a PC and continuing the forecast work. The AIDSFIX method has proved itself very accurate in forecasting AIDS and has also provided the DOH and the CJD Surveillance Unit in Edinburgh with useful projections for variant CJD. It could be extremely useful in providing early projections if new epidemics such as SARS, drug resistant TB, Avian influenza or Ebola virus should occur in the UK. 2) MOST IMPORTANT FINDING Until the end of 1999 the projections for cumulative cases of HIV in the UK were steady at around 53,000 by end-2005, 67,000 by end 2020, 80,000 by end-2015 and 95,000 by end-2020. Since then, quarter by quarter, the projections increased until the end of 2003. The straightforward projections, at the end of 2004, indicate 76,300 UK HIV cases by end-2005, 123,000 by end-2010, 184,000 by end-2015 and 257,000 by end-2020. ( see Figures 2 & 3 ) The graph of this growth is shown on Figure 3. Using the AIDSFIX program, it has been extended to show the numbers of cases that could be in the UK at the given dates if the projections in Figures 4 & 5 are reached. However, the very pessimistic projections of Report No. 13 did not come to pass and it looks as though the data have stabilised. Growth is mainly in the heterosexual population now and, if it penetrates deeply among careless promiscuous young people, large increases in the numbers of heterosexual cases of HIV could be expected. It happened in Africa and could happen in the UK. Data on HIV cases from Africa have been included in this report Clearly the whole situation needs to be kept under close scrutiny as large numbers of HIV cases needing treatment could have devastating effects on NHS finances. Figure 4 shows these projections on a quarterly basis from 03/05 so that quarterly forecasts during 2005 on Web Site www.AIDSCJDUK.info, can be directly compared with the projections. In the 13th. report a similar range of predictions was given: fortunately, they did not come to pass. e.g. :- HIV Cases 03/04 06/04 09/04 12/04 2005 Predicted at end-2003: 78.200 79,700 81,100 82,500 Quarterly forecasts: 76,000 76,100 76,100 76,300 2015 Predicted end-2003: 196,000 208,000 220,000 289,000 Quarterly forecasts: 181,000 182,000 182,000 182,000 ( 2 )